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Brand: ProteoGenix

Glycoprotein

Host species:
Mammalian cells
Uniprot ID:
P08667
Molecular weight:
59.92kDa

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Met1–Leu524
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Glycoprotein

Product name Glycoprotein
Uniprot ID P08667
Uniprot link http://www.uniprot.org/uniprot/P08667
Expression system Eukaryotic expression
Raw Antigen Sequence MVPQALLFVPLLVFPLCFGKFPIYTIPDKLGPWSPIDIHHLSCPNNLVVEDEGCTNLSGFSYMELKVGYISAIKMNGFTCTGVVTEAETYTNFVGYVTTTFKRKHFRPTPDACRAAYNWKMAGDPRYEESLHNPYPDYHWLRTVKTTKESLVIISPSVADLDPYDRSLHSRVFPGGNCSGVAVSSTYCSTNHDYTIWMPENPRLGMSCDIFTNSRGKRASKGSETCGFVDERGLYKSLKGACKLKLCGVLGLRLMDGTWVAMQTSNETKWCPPGQLVNLHDFRSDEIEHLVVEELVKKREECLDALESIMTTKSVSFRRLSHLRKLVPGFGKAYTIFNKTLMEADAHYKSVRTWNEIIPSKGCLRVGGRCHPHVNGVFFNGIILGPDGNVLIPEMQSSLLQQHMELLVSSVIPLMHPLADPSTVFKNGDEAEDFVEVHLPDVHERISGVDLGLPNWGKYVLLSAGALTALMLIIFLMTCWRRVNRSEPTQHNLRGTGREVSVTPQSGKIISSWESYKSGGETGLGGGSGGHHHHHHHH
Molecular weight 59.92kDa
Purity estimated >85% by SDS-PAGE
Buffer 50 mM Tris-HCl pH 7.4, 150 mM NaCl, 10% glycerol, 4 mM EDTA, 1% CHAPS
Delivery condition Dry Ice
Delivery lead time in business days Europe: 5-7 working days
USA & Canada: 7-10 working days
Rest of the world: 5-12 working days
Storage condition 4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Brand ProteoGenix
Host species Mammalian cells
Fragment Type Met1-Leu524
Aliases /Synonyms /
Reference PX-P4466
Note For research use only
Molecular Constructor
Met1–Leu524
Product name Glycoprotein
Uniprot ID P08667
Uniprot link http://www.uniprot.org/uniprot/P08667
Expression system Eukaryotic expression
Raw Antigen Sequence MVPQALLFVPLLVFPLCFGKFPIYTIPDKLGPWSPIDIHHLSCPNNLVVEDEGCTNLSGFSYMELKVGYISAIKMNGFTCTGVVTEAETYTNFVGYVTTTFKRKHFRPTPDACRAAYNWKMAGDPRYEESLHNPYPDYHWLRTVKTTKESLVIISPSVADLDPYDRSLHSRVFPGGNCSGVAVSSTYCSTNHDYTIWMPENPRLGMSCDIFTNSRGKRASKGSETCGFVDERGLYKSLKGACKLKLCGVLGLRLMDGTWVAMQTSNETKWCPPGQLVNLHDFRSDEIEHLVVEELVKKREECLDALESIMTTKSVSFRRLSHLRKLVPGFGKAYTIFNKTLMEADAHYKSVRTWNEIIPSKGCLRVGGRCHPHVNGVFFNGIILGPDGNVLIPEMQSSLLQQHMELLVSSVIPLMHPLADPSTVFKNGDEAEDFVEVHLPDVHERISGVDLGLPNWGKYVLLSAGALTALMLIIFLMTCWRRVNRSEPTQHNLRGTGREVSVTPQSGKIISSWESYKSGGETGLGGGSGGHHHHHHHH
Molecular weight 59.92kDa
Purity estimated >85% by SDS-PAGE
Buffer 50 mM Tris-HCl pH 7.4, 150 mM NaCl, 10% glycerol, 4 mM EDTA, 1% CHAPS
Delivery condition Dry Ice
Delivery lead time in business days Europe: 5-7 working days
USA & Canada: 7-10 working days
Rest of the world: 5-12 working days
Storage condition 4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Brand ProteoGenix
Host species Mammalian cells
Fragment Type Met1-Leu524
Aliases /Synonyms /
Reference PX-P4466
Note For research use only
Molecular Constructor
Met1–Leu524

General Information about Glycoprotein

Attaching the virus to the host cell receptor induces endocytosis of virus particles. In endosomes, acidic pH induces conformational changes of glycoprotein trimers, which triggers the fusion between the virus and the cell membrane. There is convincing in vitro evidence that the muscle forms of nicotinic acetylcholine receptor (nAChR), neuronal cell adhesion molecule (NCAM) and p75 neurotrophin receptor (p75NTR) bind to glycoproteins, thereby promoting rabies virus entry into cells (by similarity).

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